Particle Therapy

Qualyscan® Upright

In vivo verification integrated into upright particle therapy

Qualyscan® Upright brings Positron Emission Tomography (PET) based verification directly into the treatment position, enabling accurate in vivo assess-ment of the delivered dose under real clinical conditions.

A fully integrated treatment workflow

Part of a unified ecosystem combining:

RaySearch’s treatment planning software, RayStation®
Leo Cancer Care’s upright treatment platform, Marie®
Terapet’s in vivo PET verification system, Qualyscan® Upright

This combination connects planning, treatment and in vivo verification in a single continuous workflow and enabling, for the first time, a truly end-to-end approach to treatment validation in particle therapy.

During or immediately after irradiation, PET signals from irradiated tissue are acquired in the treatment position, preserving signal integrity and minimizing biological washout. The measured activity distribution is then directly compared with the expectation from the treatment plan, providing independent and quantitative verification of treatment delivery.

Advanced PET technology

Combining high-precision detectors, radiation-tolerant electronics, and advanced reconstruction algorithms, the system is designed for reliable performance in demanding treatment conditions.
Accurate CT–PET registration and standardized data export enable seamless integration into clinical and research workflows.

Enabling the next generation of particle therapy

By bringing verification into the treatment position, Qualyscan Upright opens new possibilities for adaptive therapy, data-driven decision-making, and biologically guided treatments.